Is the life of 4 rats worth a human life? Yes. Animal research plays a crucial role in scientist’s understanding of diseases and in the development of effective medical treatments. Research animals provide scientists with complex living systems consisting of cells, tissues and organs. More than biologically similar to humans, animals are vulnerable to over 200 of the same health disorders. Therefore, they are an effective model for researchers to study, since research on animals is heavily regulated, involves lower number of animals than imagined and has brought treatments to many diseases.
Around the world, the welfare of animals in research is protected by national and international legislations, by local laws or by ethical committees. Countries, such as the USA and UK, which invest a large amount of money in their Research & Development departments, have already regulated the use of animals in medical research and they control it under the law. The UK is widely recognized as having the most comprehensive regulation concerning this issue. The Animals Act of 1986 emphasizes that no animal experiments should be conducted if a realistic alternative is available. Additionally, the benefits of it must be clearly described. Testing on animal requires 3 Licensees: for the institution, the scientist and the project. Random inspections, on-site vets and basic needs (such as comfort, shelter, enough food and water, company of other animals and treatments of injuries and diseases) are mandatory. The animals must be examined everyday and any animal judged to be in severe pain or distress that can’t be relieved must be painlessly killed. Animal research is strictly regulated: the official codes are focused in providing the animals with standards of care.
Although most people believe animal research involves a great number of killings, the statistics show the number is not that high. In terms of number, nearly 3 million animal procedures are conducted a year in UK. Compared to other statistics number, these researches involve approximately 2000 times less killings. For example, in UK, 2,5 billion of animals (cows and fish) are eaten per year, of the 6,7 million dogs and 9 million cats, there are 110000 cases of animal cruelty. Moreover, 6,3 million animals were hit by a car on UK roads and 2 million rats that invade houses are killed per year. Even though 3 million of animals used in science research seems a high number, it becomes lower when put in perspective with other animal scenarios, as food, car accidents, animal cruelty and killing.
The relevance of animal experiments is evidenced by several medical progresses occurred since the beginning of the 19th century. The use of animals in research has been a common practice since the early 1910s. Since then, scientists study animals for their differences and their similarities to humans, providing information about safety and effectiveness and, therefore, supporting the tests for new drugs. The discovery of insulin in the ’20s relieved the symptoms of diabetes, sulphonamides and antibiotics were developed to treat bacterial infections, vaccines were produced to control viral infections and surgery advanced with modern anaesthetics and heart-lung machine. In the ’50s, kidney transplants, hip replacement surgery and drugs to control high blood pressure and mental illness were developed based on animal experiments. Nowadays, new treatments of leukaemia, asthma, AIDS were discovered and studied thanks to the animals. Each of these and many other advances were critically dependent on animal research.
Since the beginning of the 19th century, at least 60 of the 90 Nobel Prizes awarded for medicine, were discoveries or advances in which laboratory animals played a crucial role. Although undeniably, the medical progress and laboratory animals are strongly related, efforts should be made to harmonize requirements of regulatory authorities around the world, in order to reduce, even more, the number of laboratory animals used. Moreover, due to the fact that medical research is a gamble, i.e., many possibilities are explored before an effective treatment is found, people should always think how to measure the chance of reducing human suffering against the certainty of inducing suffering in an animal. From an individual perspective, each person enjoys the medical benefits of animal research for the use of 3 mice and 1 rat over their entire life. Based on the medical technology available nowadays, 3 mice and 1 rat may save a human life.